Berek Novak's Gyn 2019. Chapter 21 Preventive Health Care and Screening

 CHAPTER 21

Preventive Health Care and Screening

KEY POINTS

1 Preventive health services that encompass screening and counseling for a broad range

of health behaviors and risks are important components of general obstetric and

gynecologic care.

2 Traditional gynecologic care—including cervical cytology testing, pelvic and breast

screening examinations, and the provision of contraceptive services—is considered

primary preventive care.

11283 Routine health care assessments for healthy women include a medical history,

physical examination, routine and indicated laboratory studies, assessment and

counseling regarding healthy behaviors, and relevant interventions, taking into

account the leading causes of morbidity and mortality within different age groups.

4 Through the Women’s Preventive Services Initiative (WPSI), the American College

of Obstetricians and Gynecologists (ACOG) is coordinating with the U.S.

Department of Health and Human Services (HHS) to develop and update

recommendations for women’s preventive health services.

5 Obesity, smoking, and alcohol abuse are preventable problems that have a major

impact on long-term health; assessment, counseling, and referral for these health

risks is a component of periodic health assessment and primary care.

[1] Although obstetrician-gynecologists are specialists in caring for women

during pregnancy and adeptly manage abnormal gynecologic conditions,

they also have a traditional role of providing primary and preventive care to

women, particularly for women of reproductive age. Preventive health

services that encompass screening and counseling for a broad range of health

behaviors and risks are important components of general obstetric and

gynecologic care. The obstetrician-gynecologist often serves as a woman’s point

of entry into the health care system, her primary care clinician, and a source of

continuity of care (1).

Primary care emphasizes health maintenance, preventive services, early

detection of disease, and availability and continuity of care. Women often regard

their gynecologist as their primary care provider; indeed, many women of

reproductive age have no other physician. Obstetrician-gynecologists estimated

that at least one-third of their nonpregnant patients rely on them for primary care

(2). [2] As primary care physicians, obstetrician-gynecologists provide

ongoing care for women through all stages of their lives—from the

reproductive age to postmenopause. Many services provided as part of

traditional gynecologic care, including cervical cytology testing, pelvic and

breast screening examinations, and the provision of contraceptive services,

are considered primary preventive care. Some gynecologists include screening

for certain medical conditions, such as hypertension, diabetes mellitus, and

thyroid disease, and management of those conditions in the absence of

complications, as a routine part of their practices.

Some traditional aspects of gynecologic practice, such as family planning and

preconception counseling, are recognized as key Healthy People 2020 goals (3).

Culturally appropriate evidence- and competency-based clinical guidelines are

lacking in the United States, and preventing unintended pregnancies remains an

elusive goal (4). Preventive medical services encompass screening and counseling

1129for a broad range of health behaviors and risks, including sexual practices;

prevention of sexually transmitted diseases (STDs); the use of tobacco, alcohol,

and other drugs; diet; and exercise.

While promoting preventive health care can lead to significant improvements

in the overall health, it remains a challenging task for many physicians, as they

must prioritize which of the numerous preventive services to recommend and

incorporate into everyday practice. Preventive care is often provided in

conjunction with an entire team of clinicians, including other specialists,

subspecialists, and allied health professionals. In general, the approach to

promoting preventive health care in clinical practice is to tailor services to

individual patients based upon the age, lifestyle habits, medical and family

history, and other risk factors.

Effectively communicating and explaining the relevant recommendations and

the harms of inappropriate screening are equally important and crucial to the

provision of preventive health. In a population-based cohort study, the existence

of a patient’s connection to a physician was more closely associated with the

receipt of various levels of preventive care, than race or ethnicity (5). A team

approach that extends beyond reliance on the clinician and incorporates all staff

of an office system to facilitate reminders and provide patient information can be

a very successful strategy for the timely delivery of quality preventive care

services.

GYNECOLOGIST AS A PRIMARY CARE PROVIDER

The obstetrician-gynecologist frequently serves as a primary medical resource for

women and their families, providing information, [3] guidance, and referrals

when appropriate. Routine health care assessments for healthy women are

based on age groups and risk factors. Health guidance takes into account the

leading causes of morbidity and mortality within different age groups. Patient

counseling and education require an ability to assess individual needs, assess

stages of readiness for change, and use good communication skills, including

motivational interviewing to encourage behavioral changes and ongoing care (6).

A team approach to care is frequently helpful, utilizing the expertise of medical

colleagues, such as nurses; advanced practice nurses, including nurse midwives

and nurse practitioners; health educators; other allied health professionals, such as

dieticians or physical therapists; relevant social services; and other physician

specialists. All clinicians, regardless of the extent of their training, have

limitations to their knowledge and skills and should seek consultation at

appropriate times for the benefit of their patients in providing reproductive and

nonreproductive care.

1130The National Ambulatory Medical Care Survey (NAMCS), conducted by the

Centers for Disease Control and Prevention’s (CDC) National Center for Health

Statistics is an annual nationally representative survey of visits to nonfederal

office-based patient care physicians. It defines obstetrician-gynecologists among

primary care providers, as opposed to medical or surgical subspecialists (7). In

2012, it was estimated that there were 929 million physician office visits. The

visit rate for women aged 18 to 64 years (321 visits per 100 women) was 57%

higher than the rate for men aged 18 to 64 years (204 per 100 men) (8).

Women’s needs for primary care vary across their lifespan. One survey of

women’s satisfaction with primary care found that women in their early

reproductive years (ages 18 to 34) were more satisfied with care coordination and

comprehensiveness when their regular provider was a reproductive health

specialist, primarily an obstetrician-gynecologist physician as compared to a

generalist, a generalist clinician plus an obstetrician-gynecologist, or no regular

provider (9). The scope of services provided by obstetrician-gynecologists varies

from one practice or clinician to another and may include more or fewer aspects

of well-woman and reproductive health care. It is important to establish with each

patient whether she has another primary care clinician, and who will be providing

which primary care and preventive health services (1). In 2014, routine prenatal

and gynecologic examinations were among the leading principal reasons for care

(7).

When asked to characterize the nature of an office or clinic visit, obstetriciangynecologists may or may not identify themselves as primary care providers,

depending on a number of variables (10). Those variables may include the

patient’s age, pregnancy status, whether it is a new versus a return visit,

diagnoses, insurance or referral status, and geographic practice region.

APPROACHES TO PREVENTIVE CARE

In health care, the focus is shifting from disease to prevention. Preventive care—

including reproductive life planning, optimization of nutrition and exercise,

screening for and management of chronic diseases, immunizations, management

of infectious diseases, and attention to psychological and behavioral health—

contributes to women’s overall health. Efforts are under way to promote effective

screening measures that can have a beneficial effect on public and individual

health.

To ensure that women of all ages receive appropriate preventive health

screenings, health care providers and patients need uniform, established

guidelines for recommended preventive services for women.

The Institute of Medicine’s July 2011 report noted a perceived lack of

1131transparency in the derivation of certain clinical practice recommendations and in

managing conflicts of interest (11). Variations in the guidelines’ development

processes were felt to be a fundamental cause of the lack of consistent guidelines

across specialties and groups, such as the American College of Obstetricians and

Gynecologists (ACOG), National Comprehensive Cancer Network (NCCN) and

U.S. Preventive Services Task Force (USPSTF). These discrepancies were

thought to contribute to provider uncertainty and patient confusion.

In 2016, in response to this concern over inconsistent recommendations,

ACOG launched the Women’s Preventive Services Initiative (WPSI). [4]

Through a 5-year cooperative agreement with the U.S. Department of Health

and Human Services (HHS), Health Resources and Services Administration

(HRSA), ACOG will coordinate the WPSI effort to develop, review, update

and disseminate recommendations for women’s preventive health care

services. WPSI aims to promote thorough consideration of the best available

evidence, ensure transparency and minimize the impact of individual bias, and

conflicts of interest.

An advisory panel consisting of representatives from the ACOG, American

Academy of Family Physicians (AAFP), the American College of Physicians

(ACP), and the National Association of Nurse Practitioners in Women’s Health

(NPWH) oversees the initiative. Representatives from many medical specialty

societies and national health professional organizations listed in Table 21-1

constitute the Multidisciplinary Steering Committee (MSC).

Recommendations presented by the WPSI follow the criteria specified by the

National Academies of Sciences, Engineering and Medicine (formerly the

Institute of Medicine). Topics considered by the WPSI focus on specific evidence

gaps and new recommendations not covered by existing recommendations from

the USPSTF, the American Academy of Pediatrics (AAP) Bright Futures

Initiatives for infants, children, and adolescents, and the CDC’s Advisory

Committee on Immunization Practices (ACIP).

Table 21-1 Women’s Preventive Services Initiative 2016 Multidisciplinary Steering

Committee Participating Organizations

American Academy of Family

Physicians

American Osteopathic Association

American College of Obstetricians and

Gynecologists

American Psychiatric Association

American College of Physicians American Geriatrics Society

National Association of Nurse Association of Reproductive Health

1132Practitioners in Women’s Health Professionals

Academy of Women’s Health Association of Women’s Health,

Obstetric and Neonatal Nurses

American Academy of Pediatrics National Comprehensive Cancer

Network

American Academy of Physician

Assistants

National Medical Association

American Cancer Society Association of Maternal and Child

Health Programs

American College of Nurse-Midwives National Partnership for Women and

Families

American College of Preventive

Medicine

National Women’s Law Center

American College of Radiology Patient Representative

Source: Women’s Preventive Services Initiative. Final recommendations: preventive

services for women. In: Recommendations for preventive services for women. Final report

to the U.S. Department of Health and Human Services, Health Resources & Services

Administration, December 2016. Washington, DC: American College of Obstetricians and

Gynecologists; 2017:8.

Reviews and updates of the evidence for each topic under consideration were

carefully undertaken. The scope of updates was based on Populations,

Interventions, Comparators, Outcomes, Timing and Setting/Study Design

(PICOTS) format. Searches were conducted in Ovid MEDLINE, the Cochrane

Central Register of Controlled Trials, the Cochrane Database of Systematic

Reviews, and PsycINFO. Studies conducted in settings applicable to the United

States were particularly targeted. Recommendations were adopted only if 75%

agreement was reached by the Multispecialty Steering Committee. In general,

recommendations apply to the general population of women in the United States

at average risk for the conditions addressed.

One of the research gaps includes lack of sufficient evidence for tailoring many

of the recommendations to the specific needs of racial and ethnic minority women

and underserved populations.

Guidelines for Primary and Preventive Care

1133The initial evaluation of a patient involves a complete history, physical

examination, routine and indicated laboratory studies, evaluation and counseling,

appropriate immunizations, and relevant interventions. Risk factors should be

identified and arrangements should be made for continuing care or referral, as

needed.

In its first year, the WPSI updated nine topics (12).

In the subsequent 4 years, various subcommittees will be tasked with

developing recommendations on one to two topics each year. The WPSI

preventive services recommendations are presented in a single website,

http://www.WomensPreventiveHealth.org. Recommendations will be reviewed

for currency and accuracy at least every 24 months after submission to and

adoption by HRSA.

Guide to Clinical Preventive Services

The USPSTF was commissioned in 1984 as a 20-member nongovernmental panel

of experts in primary care medicine, epidemiology, and public health. The

USPSTF, comprising primary care providers, now includes nonfederal experts in

prevention and evidence-based medicine (such as internists, pediatricians, family

physicians, gynecologist-obstetricians, nurses, and health behavior specialists);

the task force conducts and publishes scientific evidence reviews on a variety of

preventive health services with administrative and research support from the

Agency for Health Care Research and Quality (AHRQ). Initial and subsequent

reviews and recommendations are being revised and periodically released on the

website sponsored by the AHRQ (13). The charge to the panel was to develop

recommendations for the appropriate use of preventive interventions based on a

systematic review of evidence of clinical effectiveness. The panel was asked to

rigorously evaluate clinical research to assess the merits of preventive measures,

including screening tests, counseling, immunizations, and medications.

The task force uses systematic reviews of the evidence on specific topics in

clinical prevention that serve as the scientific basis for recommendations. The

task force reviews the evidence, estimates the magnitude of benefits and harms,

reaches consensus about the net benefit of a given preventive service, and issues a

recommendation that is assigned a grade from “A” (recommends; net benefit

substantial), to “B” (recommends; net benefit moderate), “C” (recommends;

selectively), “D” (recommends; against), “I” (insufficient evidence to recommend

for or against) (Table 21-3). The grading system includes suggestions for

practice, recommending that the service should be provided, discouraged, or that

the uncertainty about the balance of benefits versus harms should be discussed.

The task force evaluates services based on age, gender, and risk factors for

disease, making recommendations about which preventive services should be

1134included in routine primary care for which populations. Primary preventive

measures are those that involve intervention before the disease develops, such as

quitting smoking, increasing physical activity, eating a healthy diet, quitting

alcohol and other drug use, using seat belts and receiving immunizations.

Secondary preventive measures are those used to identify and treat asymptomatic

persons who have risk factors or preclinical disease but in whom the disease itself

has not become clinically apparent. Examples of secondary preventive measures

are well known in gynecology, such as screening mammography and cervical

cytology testing.

Table 21-2 Women’s Preventive Services Initiative Clinical Recommendations 2016

Topic Recommendation

Breast cancer

screening for

average-risk

women

• Initiate mammography screening no earlier than age 40 and no later

than age 50. Screening mammography should occur at least

biennially and as frequently as annually. Screening should

continue through at least age 74 and age alone should not be the

basis to discontinue screening.

Breastfeeding

services and

supplies

• Recommends comprehensive lactation support services (including

lactation counseling, education and breastfeeding equipment, and

supplies) during the antenatal, perinatal, and postpartum periods.

• Access to double electric breast pumps should be based on

optimization of breastfeeding, and not predicated on prior failure

of a manual pump.

Screening for

cervical

cancer

• Recommends cervical cancer screening for average-risk women

aged 21 to 65 years.

• Recommends screening with cytology alone every 3 years for

women aged 21 to 29 years.

• Recommends screening with cytology and human papillomavirus

every 5 years or cytology alone every 3 years for women aged 30

to 65.

• Cervical cancer screening is not recommended for women younger

than 21 years or those older than 65 with adequate prior screening.

Adequate prior negative screening is defined as three consecutive

negative cytology results or two consecutive negative cotest results

within the previous 10 years with the most recent test within the

past 5 years.

Contraception • Recommends the full range of female-controlled U.S. FDA-

1135approved contraceptive methods, effective family planning

practices, and sterilization procedures be available as part of

contraceptive care.

• Recommends timely authorization of contraceptives.

• Emphasizes patient-centered decision making and allows for

discussion of full range of contraceptive options.

Screening for

gestational

diabetes

mellitus

• Recommends screening pregnant women for gestational diabetes

mellitus after 24 weeks of gestation (preferably between 24 and 28

weeks of gestation).

• Recommends screening with a 50-g oral glucose challenge test

(followed by a 100-g 3-hour glucose tolerance test if results on the

initial glucose challenge test are abnormal).

Screening for

HIV infection

• Recommends prevention education and risk assessment for HIV

infection in adolescents and women at least annually throughout

the lifespan.

• Recommends all women be tested at least once during their

lifetime.

• Screening for HIV is recommended for all pregnant women upon

initiation of prenatal care.

• Rapid HIV testing is recommended for pregnant women who

present in active labor with an undocumented HIV status.

• Risk factors for HIV infection in women include, but are not

limited to: being an active injection drug user; having unprotected

vaginal or anal intercourse; having multiple sexual partners;

initiating a new sexual relationship; having sexual partners who are

HIV-infected, bisexual, or injection drug users; exchanging sex for

drugs or money; being a victim of sex trafficking; being

incarcerated (currently or previously); and having other sexually

transmitted infections (STIs).

Screening for

interpersonal

and domestic

violence

• Recommends screening adolescents and women for interpersonal

and domestic violence, at least annually.

• Interpersonal and domestic violence includes physical violence,

sexual violence, stalking and psychological aggression (including

coercion), reproductive coercion, neglect and the threat of

violence, abuse, or both.

• Risk factors for interpersonal and domestic violence include but are

not limited to pregnancy; younger and older age; increased stress;

lesbian, gay, bisexual, transgender, and queer (or questioning)

1136status; dependency; drug and alcohol misuse former or current

military service; and living in an institutional setting.

• Minimum screening intervals are unknown.

Counseling

for STIs

• Recommends directed behavioral counseling by a health care

provider or other appropriately trained individual for sexually

active adolescent and adult women at an increased risk for STIs.

• Risk factors include age younger than 25; a recent history of an

STI; a new sex partner; multiple partners; a partner with concurrent

partners; a partner with an STI; and lack of or inconsistent condom

use.

Well-woman

preventive

visits

• Recommends that women receive at least one preventive visit per

year beginning in adolescence and continuing across the lifespan.

Source: Women’s Preventive Services Initiative. Final recommendations: preventive

services for women. In: Recommendations for preventive services for women. Final report

to the U.S. Department of Health and Human Services, Health Resources & Services

Administration, December 2016. Washington, DC: American College of Obstetricians and

Gynecologists; 2017:17–23.

The USPSTF has recognized that for certain issues in medicine, evidence from

randomized controlled trials (RCT) are lacking and that it is necessary to consider

evidence from other study designs. Nevertheless, even when incorporating

evidence from non-RCT studies, insufficient evidence remains a limitation. As

clinicians do not have the luxury of waiting for certain evidence, the USPSTF

acknowledges the importance of four different “domains” when making clinical

decisions about prevention. The four domains pertinent to the decision-making

process are the preventable burden of suffering from a particular condition,

potential harm of an intervention, monetary and opportunity costs of a particular

service, and current practice landscape (15).

Table 21-3 U.S. Preventive Services Task Force Ratings

The U.S. Preventive Services Task Force (USPSTF) grades its recommendations

according to one of five classifications (A, B, C, D, I) reflecting the strength of

evidence and magnitude of the net benefit (benefits minus harms). The USPSTF

changed its grade definitions based on a change in methods in May 2007 and again in

July 2012, when it updated the definition of and suggestions for practice for the grade

C recommendation (14).

Grade Definition Suggestions for Practice

1137A The USPSTF recommends the service.

There is high certainty that the net

benefit is substantial.

Offer or provide this service

B The USPSTF recommends the service.

There is high certainty that the net

benefit is moderate or there is

moderate certainty that the net benefit

is moderate to substantial.

Offer or provide this service

C The USPSTF recommends selectively

offering or providing the service to

individual patients based on

professional judgment and patient

preferences. There is at least moderate

certainty that the net benefit is small.

Offer or provide this service

for selected patients depending

on individual circumstances

D The USPSTF recommends against the

service. There is moderate or high

certainty that the service has no net

benefit or that the harms outweigh the

benefits.

Discourage the use of this

service

IS

tatement

The USPSTF concludes that the

current evidence is insufficient to

assess the balance of benefits and

harms of the service. Evidence is

lacking, of poor quality, or conflicting,

and the balance of benefits and harms

cannot be determined.

Read the clinical

considerations section of the

USPSTF Recommendation

Statement. If the service is

offered, patients should

understand the uncertainty

about the balance of benefits

and harms.

International efforts to categorize the effectiveness of treatments include the

Cochrane Library, which produces and disseminates high-quality systematic

reviews of health care interventions. Their reviews and abstracts are published

monthly and are available online and on DVDs by subscription (16). The

Cochrane Library provides searchable databases online and through institutional

purchase of licenses. Evidence-based guidelines are published in journals

available in print and online by discipline (i.e., medicine, mental health, and

nursing).

Counseling for Health Maintenance

During periodic assessments, patients should be counseled about preventive care

1138based on their age and risk factors. [5] Obesity, smoking, and alcohol abuse are

associated with preventable problems that can have major long-term impacts

on health. Patients should be counseled about smoking cessation and moderation

in alcohol use and directed to appropriate community resources as necessary.

Positive health behaviors, such as eating a healthy diet and engaging in regular

exercise, should be reinforced. Adjustments may be necessary based on the

presence of risk factors and the woman’s current lifestyle and condition. Efforts

should focus on weight control, cardiovascular fitness, and reduction of risk

factors associated with cardiovascular disease and diabetes (6).

Nutrition

Patients should be given general nutritional information and referred to other

professionals if they have special needs (6). Assessment of the patient’s body

mass index (BMI) = weight (in kilograms) divided by height (in meters) squared

(kilograms per square meter) will give valuable information about the patient’s

nutritional status. Tables and apps (applications) to calculate BMI are available in

print and electronic resources. Patients who are 20% above or below the normal

range require evaluation and counseling and should be assessed for systemic

disease or an eating disorder. From 2013 to 2014, the overall age-adjusted

prevalence of obesity was 40.4% (95% CI; 37.6%–43.3%) among adult women

(17). In 2017, all states had more than 20% of adults with obesity. The South had

the highest prevalence of obesity (32.4%), followed by the Midwest (32.3%), the

Northeast (27.7%) and the West (26.1%) (18). Overweight and obesity

substantially increase the risk of morbidity from hypertension, dyslipidemia, type

2 diabetes, coronary artery disease, stroke, gallbladder disease, osteoarthritis,

sleep apnea, and cancers of the endometrium, breast, and colon (19).

Central obesity—measured as the waist-to-hip ratio—is an independent risk

factor for disease. Women with a waist circumference greater than 35 in are at

higher risk of diabetes, dyslipidemia, hypertension, and cardiovascular disease

(20). Metabolic syndrome is a complication of obesity that, while somewhat

variably defined, includes a clustering of atherogenic dyslipidemia, elevated

blood pressure, elevated plasma glucose, and abdominal obesity and confers an

increased risk for cardiovascular disease and diabetes (21). One-third to one-half

of premenopausal women with polycystic ovarian syndrome (PCOS) meet the

criteria for metabolic syndrome (22).

1139FIGURE 21-1 MyPlate icon. This is a new communications initiative based on the 2010

Dietary Guidelines for Americans, replacing the Food Pyramid. It is designed to remind

Americans to eat healthfully, and illustrates the five food groups using a familiar mealtime

visual of a place setting. (From the U.S. Department of Agriculture,

http://www.choosemyplate.gov)

Every 5 years, the U.S. Department of Agriculture (USDA) and (HHS) jointly

publish a report containing nutritional and dietary information and guidelines for

the general public, with the 2015–2020 Dietary Guidelines for Americans being

the most current edition (23). The guidelines provide evidence-based food and

beverage recommendations for Americans aged 2 years and older with aims to

promote health, prevent chronic disease, and help people reach and maintain a

healthy weight. The Dietary Guidelines recommend including a variety of

vegetables, fruits, grains, fat-free or low-fat dairy, a variety of proteins and oils as

1140part of a healthy eating pattern. The MyPlate symbol is a useful tool to bring

together the key elements of healthy eating patterns, translating the Dietary

Guidelines into key consumer messages that are used in educational materials for

the public (Fig. 21-1) (23). The guidelines include recommendations to balance

food and physical activity and stay within daily calorie requirements.

Fiber content of the diet is being studied for its potential role in the prevention

of several disorders, particularly colon cancer. It is recommended that the average

diet for adult women contain 22 to 28 g of fiber per day (23). Whole-grain foods

and vegetables, citrus fruits, and some legumes, are high in fiber and are

emphasized in the guidelines for healthy foods.

Adequate calcium intake is important in the prevention of osteoporosis. A

postmenopausal woman should ingest 1,200 mg per day. Adolescents require

1,300 mg per day. Because it may be difficult to ingest an adequate amount of

calcium daily in an average diet, supplements may be required.

The U.S. Public Health Service has recommended that women of reproductive

age who are capable of becoming pregnant take supplemental folic acid (0.4 mg

daily) to help prevent neural tube defects in their infants. Surveys indicate that in

2007, 40% of women of childbearing age consumed a supplement, a percentage

that is only half of the Healthy people 2010 objective of 80% (24). Women who

are contemplating pregnancy should be counseled about the risk of fetal neural

tube defects and the role of folic acid supplementation in their prevention prior to

conception (25).

Alcohol

Alcoholic beverages, if consumed, should be done so in moderation—up to one

drink per day for women (23). A simple device called the T-ACE questionnaire

(Tolerance; been Annoyed by criticism of drinking; felt need to Cut down; need

for Eye-opener) can be used to elicit information about alcohol use and identify

problem drinkers (26). Women should be questioned in a nonjudgmental fashion

about their alcohol use and directed to counseling services as required.

Exercise

Exercise can help control or prevent hypertension, diabetes mellitus,

hypercholesterolemia, and cardiovascular disease and helps to promote the overall

good health, psychological well-being, and a healthy body weight. Moderate

exercise along with calcium supplementation can help retard bone loss in

postmenopausal women. Physical activity, adequate nutrition, and good health are

necessary for bone health (27). Exercise helps promote weight loss, strength and

fitness, and stress reduction. Federal exercise guidelines from the HHS note that

“regular physical activity reduces the risk of many adverse health outcomes; some

1141physical activity is better than none; for most health outcomes, additional benefits

occur as the amount of physical activity increases through higher intensity,

greater frequency, and/or longer duration; most health benefits occur with at least

150 minutes (2 hours and 30 minutes) a week of moderate-intensity physical

activity, such as brisk walking. Additional benefits occur with more physical

activity; both aerobic (endurance) and muscle-strengthening (resistance) physical

activity are beneficial; health benefits occur for children and adolescents, young

and middle-aged adults, older adults, and those in every studied racial and ethnic

groups; the health benefits of physical activity occur for people with disabilities;

and the benefits of physical activity far outweigh the possibility of adverse

outcomes” (28). Cardiovascular conditioning, stretching exercises for flexibility,

resistance exercises, or calisthenics for muscle strength and endurance are

recommended for most people. Older adults (65 years and older) should do

exercises that maintain or improve balance if they are at risk of falling and should

determine their level of effort for physical activity relative to their level of fitness

(23). Factors that should be considered in establishing an exercise program

include medical limitations, such as obesity or arthritis, and careful selection of

activities that promote health and enhance compliance (1).

Cardiovascular fitness can be evaluated by measurement of heart rate during

exercise. As conditioning improves, the heart rate stabilizes at a fixed level. The

heart rate at which conditioning will develop is called the target heart rate (1). The

American Heart Association recommends calculation of maximum heart rate

using the formula 220 - age. Target heart rate should range from 50% to 70% for

moderate exercise and 70% to 85% for strenuous exercise (29). A 2010 study

examined the definition of a normal heart rate response to exercise stress testing

in women and noted that the traditional male-based calculation of target heart rate

may not be appropriate for women (30). The alternative formula for target heart

rate, based on this research, is 206 - (patient’s age × 0.88).

Smoking Cessation

Smoking is a major cause of preventable illness, and every opportunity should be

taken to encourage patients who smoke to quit. Patient education about the

benefits of smoking cessation, clear advice to quit smoking, and physician

support improve smoking cessation rates, although 95% of smokers who

successfully quit do so on their own. Self-help materials are available from the

National Cancer Institute, and community-based support groups and local

chapters of the American Cancer Society and the American Lung Association.

The combination of counseling and medication (nicotine and non-nicotine

options) is more effective than either used alone, and Clinical Practice Guidelines

on treating tobacco use, and dependence from the HHS provide recommendations

1142(31).

The “5 As”—Ask, Advise, Assess, Assist, and Arrange—are designed to be used

with smokers who are willing to quit (32). The Ask component involves

systematically identifying all tobacco users at every visit. It is important that the

advice given to urge tobacco users to quit is clear, strong, and personalized. Next,

providers should assess a patient’s willingness to quit and provide assistance if

applicable or provide an intervention to increase future quit attempts. In 2015, the

USPSTF released evidence-based recommendations for behavioral and

pharmacologic interventions to help people quit smoking. Patient-centered

outcomes research strongly supports the use of behavioral interventions alone or

in combination with pharmacotherapy. All pregnant women who smoke should

receive behavioral interventions (33). Relapse prevention is important, with

congratulations for any successes and encouragement to remain abstinent.

Patients who use tobacco but are unwilling to quit at the time of the visit should

be treated with the “5 Rs” motivational intervention: Relevance, Risks, Rewards,

Roadblocks, and Repetition (31).

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