Gestational Trophpblastic Diseases (GTD)

 Gestational Trophpblastic Diseases (GTD)

Dr. Jennifer Anh Nguyen

1. Accurate diagnosis of Hydatiform mole can be made by

A. Elevated β-hCG

B. Ultrasound

C. Pelvic examination

D. Chest radiography

E. Absence of fetal heart in a 16 week sac

2. Risk Factors of gestational trophoblastic disease include all of the following, EXCEPT:

A. Far East Asian

B. age under 20

C. Diet high Folic acid

D. Age above 40

E. Diet lower beta carotene

3. In complete Hydatiform mole:

A. Rarely contains maternal genetic material

B. Can present with hypothyroidism

C. Prophylactic cytotoxic therapy should be given

D. Diagnosis is confirm with a very low blood level of human β Gonadotropins

E. Pre-eclampsia is the most common symptom and occur in 97% of patients

4. Definitive initial therapy for Hydatiform mole is most commonly:

A. Evacuation.

B. Abdominal hysterectomy.

C. Evacuation followed by Methotrexate therapy.

D. Evacuation followed by hysterectomy.

E. Radiation.

5. Evacuation of Hydatiform mole may be complicated by:

A. Hemorrhage necessitating transfusion.

B. Acute respiratory distress.

C. Both.

D. Neither.

6. After the β-hCG titer becomes undetectable, the patient treated for Hydatiform mole should be followed with monthly titers for a period of:

A. 3 months.

B. 6 months.

C. 1 year.

D. 2 years.

E. 5 years.

7. What is the most frequent site for metastasis from a malignant gestational trophoblastic neoplasms:

A. Brain.

B. Liver.

C. Kidneys.

D. Vulva.

E. Lung. (cannon balls appearance).

8. If you find that a 25 –year- old patient with amenorrhea of 18 weeks duration had an elevated serum hCG, and absent fetal heart & movement and uterine size 28 weeks which of the following would be the most likely diagnosis ?

A. Normal pregnancy

B. Hydatiform mole

C. Twin pregnancy

D. Missed abortion

E. Ovarian carcinoma (primary)

9. Signs and symptoms of Hydatiform mole include the following EXCEPT :

A. 1st trimester bleeding

B. A Uterus larger than expected gestational age

C. Hypothyroidism

D. Pre-eclampsia

E. Nausea and vomiting

10. Hydatiform mole is characterized by all of the following EXCEPT:

A. Theca-lutein cyst of the ovary.

B. Severe Hyperemesis.

C. Uterus larger than date.

D. Hyperthyroidism.

E. Elevated maternal blood sugar level.

11. Choriocarcinomas can occur:

A. After abortion.

B. Spontaneously.

C. After Hydatiform mole.

D. After normal pregnancy.

E. All of the above.